Management of drug-resistant TB in patients with HIV co-infection

Management of drug-resistant TB in patients with HIV co-infection

The World Health Organization estimates that 450,000 cases of drug-resistant (DR) tuberculosis (TB) occurred worldwide in 2012. In South Africa, over 15,000 cases were diagnosed. Over half of patients in South Africa with TB are HIV co-infected. The management of drug-resistant TB is complex, prolonged, costly, associated with multiple toxicities and thus difficult for patients to complete. Dis...

Thoracic CT Scan Findings in Patients with HIV/TB co-infection before and after treatment

Background and Aim: Pulmonary tuberculosis (TB) infection is common in patients infected with the Human immunodeficiency virus (HIV). In this study, we evaluated thoracic CT scan findings of HIV/TB co-infection, before and after anti-TB treatment. Materials and Methods: In this retrospective cross-sectional study, pre-and post-treatment thoracic CT scans of patients diagnosed with HIV and defin...

HIV-TB co-infection: epidemiology, diagnosis & management.

HIV/AIDS pandemic has caused a resurgence of TB, resulting in increased morbidity and mortality worldwide. HIV and Mycobacterium tuberculosis have a synergistic interaction; each accentuates progression of the other. Clinical presentation of TB in early HIV infection resembles that observed in immunocompetent persons. In late HIV infection, however, TB is often atypical in presentation, frequen...

Management of co-infection with HIV and TB.

About a third of the 36 million people living with HIV worldwide are co-infected with mycobacterium tuberculosis; 70% of those coinfected live in sub-Saharan Africa. In developing countries half of people with HIV infection will develop active tuberculosis; in some countries in sub-Saharan Africa more than 70% of patients with active tuberculosis are also HIV seropositive. Tuberculosis is the l...

Management of Drug-Resistant TB